Biomarker Assays
Alta has validated a select group of biomarkers that might be useful in the selection of a lead compound, determining the mechanism of action of a compound, used as a surrogate endpoint for demonstrating efficacy, or for identifying intermediate endpoints of success to decrease follow-up time with a specific treatment. These assays have been put through an extensive method validation and the samples are run according to GLP.
List of Validated Biomarkers:
| Biomarker |
Matrix(Matrices) |
sTNF R-II
Adioponectin
AvastinTM
BAP (Bone specific Alkaline Phosphatase)
CD-44
E-selectin
FGF
HGF
ICAM-1
IL-2
IL-6
IL-8
Leptin
MCP-1
MMP-2
MMP-3 (total)
MMP-9
MMP-gelatinase
NTX (N-telopeptide)
P selectin
TIMP-1
TNF-alpha
VCAM-1
VEGF
VEGF R2 |
Human Sodium Heparin Plasma
Human Serum, Human EDTA Plasma
Human Heparinized Plasma, Human Serum
Human Serum
Human EDTA Plasma
Human Heparinized Plasma, Human EDTA Plasma
Human EDTA Plasma
Human Heparinized Plasma, Human Serum
Human EDTA Plasma
Human Sodium Heparin Plasma
Human Sodium Heparin Plasma, Human Serum
Human Sodium Heparin Plasma
Human Serum and EDTA Plasma
Human EDTA Plasma
Human EDTA Plasma
Human Heparinized Plasma
Human Plasma, Human Serum
Human Serum
Human Serum
Human EDTA Plasma
Human Plasma
Human Sodium Heparin Plasma, Human Serum
Human EDTA Plasma
Human Serum, EDTA and Heparin Plasma
Human Heparinized Plasma, Human EDTA Plasma |
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